P5891
L-Pyroglutamic acid 2-naphthylamide
≥99% (TLC), suitable for ligand binding assays
Synonym(s):
L-Pyroglutamic acid β-naphthylamide, L-Pyrrolidonyl-β-naphthylamide, N1-(2-Naphthyl)-L-pyroglutamic acid, PYR
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About This Item
Empirical Formula (Hill Notation):
C15H14N2O2
CAS Number:
Molecular Weight:
254.28
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
244-809-9
MDL number:
Beilstein/REAXYS Number:
5066652
Product Name
L-Pyroglutamic acid 2-naphthylamide, ≥99% (TLC)
Quality Level
assay
≥99% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
2-8°C
SMILES string
O=C1CC[C@H](N1)C(=O)Nc2ccc3ccccc3c2
InChI
1S/C15H14N2O2/c18-14-8-7-13(17-14)15(19)16-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2,(H,16,19)(H,17,18)/t13-/m0/s1
InChI key
BZEPQNMASTUAMY-ZDUSSCGKSA-N
Application
A substrate for pyroglutamate aminopeptidase. Used for differentiation of Group A streptococci and enterococci from other streptococci.
Biochem/physiol Actions
Pyroglutamic acid is known to participate in the gamma-glutamyl cycle. Recent studies show that a congenital metabolic error was associated with increased pyroglutamic excretion in urine.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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Takahiro Tougan et al.
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The erythrocytic stage of Plasmodium falciparum parasites in humans is clinically important, as the parasites at this growth stage causes malarial symptoms. Most of the currently available anti-malarial drugs target this stage, but the emergence and spread of parasites resistant
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Frontiers in pharmacology, 8, 709-709 (2017-10-28)
The involvement of histamine H3 receptors (H3Rs) in memory is well known, and the potential of H3R antagonists in therapeutic management of neuropsychiatric diseases, e.g., Alzheimer disease (AD) is well established. Therefore, the effects of histamine H3 receptor (H3R) antagonist
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Parasites & vectors, 13(1), 342-342 (2020-07-11)
Parascaris univalens is a pathogenic parasite of foals and yearlings worldwide. In recent years, Parascaris spp. worms have developed resistance to several of the commonly used anthelmintics, though currently the mechanisms behind this development are unknown. The aim of this
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5891-5G | 04061834392552 |
| P5891-100MG | 04061834392514 |
| P5891-1G | 04061834392521 |
| P5891-25MG | 04061834392538 |
| P5891-500MG | 04061834392545 |