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Merck
CN

P6641

1,2-Diacyl-sn-glycero-3-phospho-L-serine solution

≥97%, from bovine brain, chloroform:methanol solution

Synonym(s):

3-sn-Phosphatidyl-L-serine, L-α-Phosphatidyl-L-serine, PS, Phosphatidylserine

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About This Item

NACRES:
NA.25
UNSPSC Code:
51191904
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biological source

bovine brain

Quality Level

assay

≥97%

form

chloroform:methanol solution

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

Application


  • Electrophoretic Light Scattering and Electrochemical Impedance Spectroscopy Studies of Lipid Bilayers Modified by Cinnamic Acid and Its Hydroxyl Derivatives.: This study explores the modification of lipid bilayers, specifically focusing on the interactions between cinnamic acid derivatives and lipid structures, including 1,2-Diacyl-sn-glycero-3-phospho-ʟ-serine solutions. It employs electrophoretic light scattering and electrochemical impedance spectroscopy to elucidate the electrochemical properties and stability of these modified bilayers, highlighting their potential in biophysical and biochemical applications (Naumowicz et al., 2020).

  • Silica-based Monolithic Capillary Columns Modified by Liposomes for Characterization of Analyte-Liposome Interactions by Capillary Liquid Chromatography.: This research investigates the use of silica-based monolithic capillary columns modified with liposomes, including 1,2-Diacyl-sn-glycero-3-phospho-ʟ-serine, to study analyte-liposome interactions. The capillary liquid chromatography technique used in this study provides insights into the behavior of analytes within lipid environments, which is crucial for understanding membrane interactions and developing lipid-based delivery systems (Moravcová et al., 2013).

Biochem/physiol Actions

A slowly metabolized structural phospholipid found mainly in gray matter.

Analysis Note

Actual concentration given on label.

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.
Solutions exposed to room temperature will decompose about 0.5% per day.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 2 - STOT SE 3

target_organs

Eyes,Central nervous system, Liver,Kidney, Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

80.1 °F - closed cup

flash_point_c

26.7 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

易制毒化学品(2类)
危险化学品

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Riccardo Provenzani et al.
PloS one, 13(4), e0195668-e0195668 (2018-04-12)
Protein kinase C (PKC) isoforms play a pivotal role in the regulation of numerous cellular functions, making them extensively studied and highly attractive drug targets. Utilizing the crystal structure of the PKCδ C1B domain, we have developed hydrophobic isophthalic acid
T I Lin et al.
Journal of virology, 75(8), 3647-3656 (2001-03-27)
The viral ion channel protein M2 supports the transit of influenza virus and its glycoproteins through acidic compartments of the cell. M2 conducts endosomal protons into the virion to initiate uncoating and, by equilibrating the pH at trans-Golgi membranes, preserves
Kwang-jin Cho et al.
The Journal of biological chemistry, 287(52), 43573-43584 (2012-11-06)
Oncogenic mutant Ras is frequently expressed in human cancers, but no anti-Ras drugs have been developed. Since membrane association is essential for Ras biological activity, we developed a high content assay for inhibitors of Ras plasma membrane localization. We discovered



Global Trade Item Number

SKUGTIN
P6641-100MG04061834393795
P6641-25MG04061834393801
P6641-5MG04061838066541