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Merck
CN

P9269

Protein A–Agarose

lyophilized powder

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About This Item

UNSPSC Code:
41106500
NACRES:
NA.56
MDL number:
Form:
lyophilized powder
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form

lyophilized powder

Quality Level

extent of labeling

~2 mg per mL

matrix

4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

capacity

≥10 mg/mL binding capacity (human IgG)

storage temp.

−20°C

General description

This Protein A-Agarose product is a conjugate of Protein A to CNBr-activated agarose without an intermediate spacer arm.

Application

Protein A-agarose is used for affinity chromatography, antibody purification and characterization, and protein A, G and L resins. Protein A-agarose has been used to study the effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy as well as to study multiple sclerosis and gastric cancer.

Physical form

Supplied as lyophilized powder stabilized with lactose.

Preparation Note

Swelling: 1 g swells to approx. 4 ml


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品

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Immune regulation in murine schistosomiasis japonica: inhibition of in vitro antigen- and mitogen-induced cellular responses by splenocyte culture supernatants and by purified fractions from serum of chronically infected mice.
K S Garb et al.
Journal of immunology (Baltimore, Md. : 1950), 129(6), 2752-2758 (1982-12-01)
Carl F Fortin et al.
International immunology, 22(8), 637-649 (2010-05-27)
Polymorphonuclear neutrophils (PMNs) are the first line of defense against invading organisms in humans; in addition, PMNs contribute to the linking of innate and adaptive immunity. To fulfill their biological behavior, PMNs utilize an arsenal of proteolytic enzymes, including members
Stefania Trazzi et al.
PloS one, 4(6), e5832-e5832 (2009-06-09)
CENP-C is a fundamental component of functional centromeres. The elucidation of its structure-function relationship with centromeric DNA and other kinetochore proteins is critical to the understanding of centromere assembly. CENP-C carries two regions, the central and the C-terminal domains, both



Global Trade Item Number

SKUGTIN
P9269-1G04061834402718
P9269-250MG04061834402749
P9269-1.5G04061834402688