P9511
3-sn-Phosphatidic acid sodium salt from egg yolk lecithin
≥98%, Phosphatidic acid precursor, powder
Synonym(s):
1,2-Diacyl-sn-glycero-3-phosphate sodium salt, L-α-Phosphatidic acid sodium salt, PA
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About This Item
Product Name
3-sn-Phosphatidic acid sodium salt from egg yolk lecithin, ≥98%
Quality Level
assay
≥98%
form
powder
storage temp.
−20°C
SMILES string
[Na+].[Na+].OC[C@@H](O)COP([O-])([O-])=O
InChI
1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;/q;2*+1/p-2/t3-;;/m1../s1
InChI key
GEKBIENFFVFKRG-HWYNEVGZSA-L
General description
Phosphatidic acid is obtained from phosphatidylcholine with the help of phospholipase D.
Application
3-sn-Phosphatidic acid sodium salt from egg yolk lecithin
- in the reaction mixture for CDS (cytidine triphosphate:phosphatidate cytidyltransferase) assay and reference lipid for thin layer chromatography (TLC)
- as a standard to compare the generated radiolabeled phosphatidic acid (PA)
- to examine its effects on At-Rac2–associated kinase activity
Biochem/physiol Actions
Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol, phosphatidic acid and lysophosphatidic acid.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases, Phosphoinositide Kinases and Phosphoprotein Phosphatases (Serine/Threonine) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
Prepared from L-α-phosphatidylcholine by hydrolysis with cabbage phospholipase D.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
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New Biotechnology, 31, 237-255 (1996)
Daniel Pastor-Flores et al.
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Pkh is the yeast ortholog of the mammalian 3-phosphoinositide-dependent protein kinase 1 (PDK1). Pkh phosphorylates the activation loop of Ypks, Tpks, Sch9 and also phosphorylates the eisosome components Lsp1 and Pil1, which play fundamental roles upstream of diverse signaling pathways
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| P9511-10MG | 04061834403395 |
| P9511-5MG | 04061833273982 |
| P9511-100MG | 04061834403388 |
| P9511-500MG | 04061833273968 |
| P9511-50MG | 04061834403487 |