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Merck
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P9544

Phosphoglucose Isomerase from rabbit muscle

Type XI, lyophilized powder, ≥200 units/mg protein

Synonym(s):

D-Glucose-6-phosphate ketol-isomerase, PGI, Phosphosaccharomutase

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About This Item

CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-603-1
MDL number:
EC Number:
Specific activity:
≥200 units/mg protein
Biological source:
rabbit muscle
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biological source

rabbit muscle

Quality Level

type

Type XI

form

lyophilized powder

specific activity

≥200 units/mg protein

composition

protein, 70-100% biuret

storage temp.

−20°C

Application

Phosphoglucose Isomerase (PGI) is an enzyme crucial for the interconversion of D-glucose 6-phosphate and D-fructose 6-phosphate. PGI is responsible for the second step of glycolysis and is involved in glucogenesis. It is highly conserved in bacteria and eukaryotes. It is used in sugar assays to convert fructose to glucose . Product 9544 is type XI and is from rabbit muscle. It is useful in enzyme systems requiring low sulfate.

Biochem/physiol Actions

Phosphoglucose Isomerase fuctions as an isomerase, neuroleukin, autocrine motility factor, and a differentiation and maturation mediator . It is responsible for the photosynthetic reduction of carbon.

Physical form

Essentially sulfate-free powder containing citrate buffer salts

Other Notes

One unit will convert 1.0 μmole of D-fructose 6-phosphate to D-glucose 6-phosphate per min at pH 7.4 at 25 °C.


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Regulatory Information

低风险生物材料

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B K Campbell et al.
Reproduction (Cambridge, England), 140(5), 721-732 (2010-08-19)
Glucose is a critical metabolic fuel in most mammals although many foodstuffs also contain high levels of the monosaccharides, galactose and fructose. The aims of this work were to determine the insulin response to challenges of these sugars (experiment 1)
C J Jeffery et al.
Biochemistry, 39(5), 955-964 (2000-02-02)
The multifunctional protein phosphoglucose isomerase, also known as neuroleukin, autocrine motility factor, and differentiation and maturation mediator, has different roles inside and outside the cell. In the cytoplasm, it catalyzes the second step in glycolysis. Outside the cell, it serves
Veera Kainulainen et al.
Journal of bacteriology, 194(10), 2509-2519 (2012-03-06)
Glutamine synthetase (GS) and glucose-6-phosphate isomerase (GPI) were identified as novel adhesive moonlighting proteins of Lactobacillus crispatus ST1. Both proteins were bound onto the bacterial surface at acidic pHs, whereas a suspension of the cells to pH 8 caused their



Global Trade Item Number

SKUGTIN
P9544-1KU04061834403746
P9544-5KU04061833493236