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PLA0125

Anti-GAPDH Antibody

rabbit polyclonal

Synonym(s):

G3PD, GAPD, GAPDH, HEL-S-162eP, aging-associated gene 9 protein, epididymis secretory sperm binding protein Li 162eP, peptidyl-cysteine S-nitrosylase GAPDH

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Species reactivity:
mouse, human
Technique(s):
immunohistochemistry: 1:100-1:500, western blot: 1:10,000-1:25,000
Application:
IHC, WB
Citations:
123
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Product Name

Rabbit anti-GAPDH Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

mouse, human

technique(s)

immunohistochemistry: 1:100-1:500, western blot: 1:10,000-1:25,000

accession no.

NP_002037.2

UniProt accession no.

P04406

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... GAPDH(2597)

Immunogen

The epitope recognized by PLA0125 maps to a region between residues 250 and 300 of human Glyceraldehyde-3-Phosphate Dehydrogenase using the numbering given in entry NP_002037.2 (GeneID 2597).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

In the process of carbohydrate metabolism, GAPDH (glyceraldehydes-3-phosphate dehydrogenase) catalyzes the oxidative phosphorylation of glyceraldehydes-3-phosphate to 1,3-diphosphoglycerate in the presence of nicotinamide adenine dinucleotide (NAD) and inorganic phosphate. In addition to its role in the oxidation of glucose, GAPDH has been shown to be involved in other cellular processes such as vesicle transport, DNA repair, DNA replication, cytoskeletal modulation, and tRNA export.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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flash_point_f

Not applicable

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
低风险生物材料

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Yoshihiro Ishikawa et al.
The Journal of biological chemistry, 296, 100453-100453 (2021-02-26)
Collagen is the most abundant protein in humans. It has a characteristic triple-helix structure and is heavily posttranslationally modified. The complex biosynthesis of collagen involves processing by many enzymes and chaperones in the rough endoplasmic reticulum. Lysyl hydroxylase 1 (LH1)
Hu-Nan Sun et al.
Molecular medicine reports, 13(6), 4927-4933 (2016-04-16)
It has previously been reported that 16α, 17α-epoxypregnenolone-20-oxime (EPREGO) exerts an inhibitory effect on nitric oxide (NO) production and inducible NO synthase (iNOS) expression in microglia. The present study aimed to investigate the effects of EPREGO on the lipopolysaccharide (LPS)‑induced
Oren Yifa et al.
JCI insight, 4(22) (2019-11-15)
The adult mammalian heart regenerates poorly after injury and, as a result, ischemic heart diseases are among the leading causes of death worldwide. The recovery of the injured heart is dependent on orchestrated repair processes including inflammation, fibrosis, cardiomyocyte survival
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Global Trade Item Number

SKUGTIN
PLA0125-100UL04061837722356