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R3030

Risperidone

Name: Risperidone
Brand: SIGMA

≥98% (HPLC), powder, antipsychotic

Synonym(s):

R 64,766

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₂₇FN₄O₂

CAS Number:

106266-06-2

Molecular Weight:

410.48

UNSPSC Code:

12352200

PubChem Substance ID:

329824020

NACRES:

NA.77

MDL number:

MFCD00274576

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

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Properties

Product Name

Risperidone, ≥98% (HPLC), powder

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥5 mg/mL

originator

Johnson & Johnson

storage temp.

room temp

SMILES string

CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1

InChI

1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3

InChI key

RAPZEAPATHNIPO-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813), HTR2A(3356), HTR2C(3358)

Description

General description

Risperidone is a benzisoxazole derivative. It functions as an antagonist for dopamine D₂, histamine H₁ and α₁ and α₂ adrenergic receptors. Risperidone is used to treat schizophrenia, bipolar disorder and autism.

Application

Risperidone has been used:

to study its effects on bone formation and differentiation
to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients
to reverse induced schizophrenia-like behavior in mice

Biochem/physiol Actions

Risperidone is an antipsychotic; serotonin-dopamine antagonist.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.