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Merck
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RAB0220

Mouse ICAM-1 ELISA Kit

for serum, plasma and cell culture supernatant

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Icam1(15894)
Input:
sample type serum
sample type plasma
sample type cell culture supernatant(s)
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 24.69-6000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Icam1(15894)

General description

The Mouse ICAM-1 (Intercellular Adhesion Molecule-1) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of mouse ICAM-1 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Mouse ICAM1

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Intercellular adhesion molecule-1 (ICAM-1) is a member of immunoglobulin (Ig) superfamily. It is an inducible transmembrane glycoprotein. ICAM-1 mediates adhesion of circulating leukocytes to the endothelial membrane and blood vessel. ICAM-1 might cause atherosclerosis and the polymorphism in ICAM-1 has reduced risk to cardiovascular diseases. IL-6 induces the upregulation of ICAM-1 and leads to metastasis of osteosarcoma cells. ICAM-1 causes invasion and metastasis of breast cancer cells. ICAM-1 is an important receptor for rhinovirus and Haemophilus influenzae binding. Upregulation of ICAM-1 in the respiratory tract of chronic airway limitation patients increases the risk of respiratory infections.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.


Kit Components Also Available Separately

Product No.
Description
SDS & Pricing

  • ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
    SDS

  • ELISA 5X Assay/Sample Diluent Buffer D (Item K)
    SDS

  • ELISA Stop Solution (Item I)
    SDS

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS

  • 20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

10 - Combustible liquids

Regulatory Information

新产品

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Certificates of Analysis (COA)

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Related Content


Role of ICAM1 in invasion of human breast cancer cells
Rosette C, et al.
Carcinogenesis, 26(5), 943-950 (2005)
IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma
Lin YM, et al.
Cancer Letters, 328(1), 135-143 (2013)
ICAM-1 gene rs5498 polymorphism decreases the risk of coronary artery disease
Liu A, et al.
Medicine, 97(40), e12523-e12523 (2018)



Global Trade Item Number

SKUGTIN
RAB0220-1KT04061834960720