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RAB0275

Mouse IL-1 β ELISA Kit

Name: Mouse IL-1 β ELISA Kit
Brand: SIGMA

for cell and tissue lysates

Synonym(s):

Cytokine detection kit

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About This Item

NACRES:

NA.32

UNSPSC Code:

41116158

Gene information:

mouse ... Il1b(16176)

Input:

sample type cell lysate
sample type tissue lysate

Species reactivity:

mouse

Storage temp.:

−20°C

Shipped in:

wet ice

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Properties

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.74-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Il1b(16176)

Description

General description

The Mouse IL-1 β ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-1 β cell lysate and tissue lysate.

Immunogen

Recombinant Mouse IL-1 β

Application

Mouse IL-1 β ELISA Kit has been used to measure the concentration of interleukin 1 (IL)1-β in serum and bronchoalveolar lavage fluid (BALF) sample.

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Interleukin 1 β (IL-1β) stimulates the production of endogenous 92 kDa gelatinase (matrix metalloproteinases 9 (MMP-9)) and tissue inhibitors of MMP (TIMP -1). It is a proinflammatory cytokine that induces various acute and chronic inflammation. Therefore, IL-1β can be considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. IL-1β brings neutrophil and macrophage to the site of infection. Over expression of IL-1β in synovial fluid contributes to the pathogenesis of synovitis and degenerative changes of the cartilaginous tissue and bone of the temporomandibular joint. Mutations in IL-1β gene leads to renal manifestations and renal sequelae in Henoch-Schonlein purpura (HSP).

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Kit Components Also Available Separately

Product No.

Description

SDS & Pricing

RABDIL6
ELISA 5X Sample Diluent Buffer (Item D2)
SDS

RABELADE
ELISA 5X Assay/Sample Diluent Buffer E (Item E2)
SDS

RABLYSIS1
2X Cell Lysis Buffer (Item J)
SDS

RABSTOP3
ELISA Stop Solution (Item I)
SDS

RABTMB3
ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
SDS

RABWASH4
20X Wash Buffer (Item B)
SDS

pictograms

GHS05

signalword

Warning

hcodes

H290

pcodes

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class

10 - Combustible liquids

Regulatory Information

低风险生物材料

常规特殊物品

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Certificates of Analysis (COA)

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Global Trade Item Number

SKU	GTIN
RAB0275-1KT	04061834961215