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Merck
CN

RAB0374

Mouse MPO ELISA Kit

for plasma and cell culture supernatant

Synonym(s):

MPO, Myeloperoxidase

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Mpo(17523)
Input:
sample type cell culture supernatant(s)
sample type plasma
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 600 pg/mL
standard curve range: 0.61-150 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Mpo(17523)

General description

The Mouse MPO (Myeloperoxidase) ELISA (Enzyme- Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MPO in plasma and cell culture supernatants.

Immunogen

Recombinant Mouse Myeloperoxidase

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Myeloperoxidase (MPO) has a crucial role to play in the destruction of various microorganisms and foreign cells, such as bacteria, fungi, viruses, red cells, and malignant and nonmalignant nucleated cells. MPO catalyzes the production of number of reactive oxidant species (ROS) that influence tissue damage during inflammation. MPO and its downstream inflammatory pathways function as a potent therapeutic target for prophylaxis of atherosclerotic cardiovascular disease. MPO catalyzes the synthesis of polychlorinated dibenzo(p)dioxins and furans (PCDD/F) from precursors such as chlorophenols in the presence of hydrogen peroxide (H2O2).

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.


Kit Components Also Available Separately

Product No.
Description
SDS & Pricing

  • ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
    SDS

  • ELISA 1X Assay/Sample Diluent Buffer C (Item L)
    SDS

  • ELISA Stop Solution (Item I)
    SDS

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS

  • 20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

10 - Combustible liquids

Regulatory Information

低风险生物材料
常规特殊物品

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Clinical manifestation of myeloperoxidase deficiency.
Lanza F, et al.
Journal of Molecular Medicine, 76, 676-681 (1998)
Maiko de Kerckhove et al.
EMBO molecular medicine, 10(10) (2018-09-02)
Argonaute 2 bound mature microRNA (Ago2-miRNA) complexes are key regulators of the wound inflammatory response and function in the translational processing of target mRNAs. In this study, we identified four wound inflammation-related Ago2-miRNAs (miR-139-5p, miR-142-3p, miR-142-5p, and miR-223) and show
Troy Perry et al.
PloS one, 12(9), e0184660-e0184660 (2017-09-19)
Ileocolic resection (ICR) is the most common intestinal resection performed for Crohn's disease, with recurrences commonly occurring at the site of the anastomosis. This study used an animal model of ICR in wild-type mice to examine immunologic changes that developed



Global Trade Item Number

SKUGTIN
RAB0374-1KT04061834962052