Skip to Content
Merck
CN

RAB0489

Human soluble TNF Receptor 1 ELISA Kit

for serum, plasma, cell culture supernatants and urine

Synonym(s):

sTNFRI

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.84
UNSPSC Code:
41116158
Gene information:
human ... TNFRSF1A(7132)
Input:
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 0.55-400 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TNFRSF1A(7132)

General description

The Human sTNF RI (soluble tumor necrosis factor receptor I) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human sTNF RI in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human TNF RI

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Tumour necrosis factor (TNF) receptor superfamily member 1A is a type I single transmembrane glycoprotein. Signal transduction mediated by binding of TNFα regulates inflammatory, immune responses and apoptotic pathway. TNF receptor 1 is implicated in the end-stage renal disease and associated mortality. Mutations in TNF receptor 1 causes autosomal dominant tumor necrosis factor receptor-associated periodic syndrome (TRAPS). Polymorphism in TNF receptor 1 causes multiple sclerosis.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.


Kit Components Also Available Separately

Product No.
Description
SDS & Pricing

  • ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
    SDS

  • ELISA 1X Assay/Sample Diluent Buffer C (Item L)
    SDS

  • ELISA Stop Solution (Item I)
    SDS

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS

  • 20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

10 - Combustible liquids

Regulatory Information

低风险生物材料
常规特殊物品

This item has



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



A novel TNFRSF1A gene mutation in a patient with tumor necrosis factor receptor-associated periodic syndrome
Khabazi A, et al.
Hematology/oncology and Stem Cell Therapy, 11(3), 175-177 (2018)
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis
Gregory AP, et al.
Nature, 488(7412), 508-511 (2012)
Circulating TNF receptors 1 and 2 predict mortality in patients with end-stage renal disease undergoing dialysis
Gohda T, et al.
Scientific Reports, 7, 43520-43520 (2017)



Global Trade Item Number

SKUGTIN
RAB0489-1KT04061834962953