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Merck
CN

RAB0797

Mouse IgA ELISA Kit

Synonym(s):

IgA, Immunoglobulin A

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

mouse

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

shipped in

wet ice

storage temp.

−20°C

General description

The antibody pair provided in this kit recognizes Mouse IgA.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Immunoglobulin A (IgA) is majorly found in the mucosal secretions. IgA exists as two subclasses, IgA1 and IgA2. IgA is a dimer in animals, but a monomer in humans. IgA interacts with the Fc fragment of IgA receptor (FCAR) to elicit immune response against inhaled pathogens. Secretory IgA (S-IgA) produced by B1 lymphocytes triggers phagocytosis and leucocyte respiratory burst. S-IgA exists as a polymer and is crucial for primary defense. The high levels of IgA in human milk and colostrum may provide immune protection to infants. Deficiency of IgA leads to increased susceptibility to infections. High levels of IgA in kidney is present in IgA nephropathy and IgA myeloma. Autoantibodies of IgA is present in celiac disease.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.


Kit Components Also Available Separately

Product No.
Description
SDS & Pricing

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS

  • ELISA Stop Solution (Item I)
    SDS

  • 20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

低风险生物材料
常规特殊物品

This item has



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Certificates of Analysis (COA)

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Shun He et al.
Nature, 566(7742), 115-119 (2019-02-01)
The biochemical response to food intake must be precisely regulated. Because ingested sugars and fats can feed into many anabolic and catabolic pathways1, how our bodies handle nutrients depends on strategically positioned metabolic sensors that link the intrinsic nutritional value
Anna-Carin Lundell et al.
Scientific reports, 7(1), 15503-15503 (2017-11-16)
Boys present with higher proportions of immature/naïve CD5
Makoto Kurano et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(4), 5181-5195 (2019-01-11)
Because the association between sphingosine 1-phosphate (S1P)/apolipoprotein M (ApoM) and chronic kidney diseases has not been established, we investigated the involvement of S1P/ApoM in the phenotypes of IgA nephropathy in hyper-IgA (HIGA) mice. The overexpression of ApoM in adenoviral gene



Global Trade Item Number

SKUGTIN
RAB0797-1KT04061835165759