Key Documents

View All Documentation

S1885

Suberic acid bis(N-hydroxysuccinimide ester)

Name: Suberic acid bis(N-hydroxysuccinimide ester)
Brand: SIGMA

≥95%, powder

Synonym(s):

Disuccinimidyl suberate, Disuccinimidyl octanedioate, Disuccinimidyl suberate (DSS)

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₆H₂₀N₂O₈

CAS Number:

68528-80-3

Molecular Weight:

368.34

NACRES:

NA.21

PubChem Substance ID:

24899500

UNSPSC Code:

12352100

MDL number:

MFCD00049059

Assay:

≥95%

Form:

powder

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

200

assay

≥95%

form

powder

reaction suitability

reagent type: cross-linking reagent

solubility

chloroform: 50 mg/mL, DMF: soluble, aqueous buffer: slightly soluble (may require 5-10% organic solvent in coupling mixture.)

functional group

imide

storage temp.

2-8°C

SMILES string

O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O

InChI

1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2

InChI key

ZWIBGKZDAWNIFC-UHFFFAOYSA-N

Description

General description

Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.

Application

Suberic acid bis(N-hydroxysuccinimide ester) has been:

supplemented in pierce lysis buffer used for immunoprecipitation
used to conjugate the oligonucleotide standards to gelatin
used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Differential oxidation of protein-tyrosine phosphatases during zebrafish caudal fin regeneration.

Wei Wu et al.

Scientific reports, 7(1), 8460-8460 (2017-08-18)

Zebrafish have the capacity to regenerate lost tissues and organs. Amputation of the caudal fin results in a rapid, transient increase in H

Quantification and calibration of images in fluorescence microscopy

Baskin DS, et al.

Analytical Biochemistry, 404(2), 118-126 (2010)

Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor

Zhou X, et al.

Cell death discovery, 5(1), 18-18 (2018)

View All Related Papers

Global Trade Item Number

SKU	GTIN
S1885-500MG	04061836915575
S1885-1G	04061836915544
S1885-5G	04061832750965