S2501
Spermidine trihydrochloride
From microbial,synthetic, ≥98% (TLC), nNOS inhibitor, powder
Synonym(s):
N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
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About This Item
Linear Formula:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
CAS Number:
Molecular Weight:
254.63
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
206-379-0
MDL number:
Beilstein/REAXYS Number:
3552356
Product Name
Spermidine trihydrochloride, ≥98% (TLC)
Quality Level
biological source
microbial, synthetic
assay
≥98% (TLC)
form
powder
mp
257-259 °C (lit.)
solubility
water: 100 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
Cl[H].Cl[H].Cl[H].NCCCCNCCCN
InChI
1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
InChI key
LCNBIHVSOPXFMR-UHFFFAOYSA-N
Gene Information
human ... NOS1(4842)
General description
The nitric oxide synthase (nNOS) gene is localized on human chromosome 12q24.22. The enzyme is involved in the production of nitric oxide.
Application
Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Disclaimer
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells.
Castro-Smirnov FA
Scientific Reports, 6, 36341-36341 (2016)
Manipulating large insert clones for transgenesis.
Sally P A McCormick et al.
Methods in molecular biology (Clifton, N.J.), 209, 105-123 (2002-10-03)
Neuronal Nitric Oxide Synthase (nNOS, NOS1) rs693534 and rs7977109 Variants and Risk for Migraine.
Garcia-Martin E
Headache, 55(9), 1209-1217 (2015)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S2501-1G | 04061836919290 |
| S2501-25G | 04061836919320 |
| S2501-5G | 04061836919443 |