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S4311

L-Serine

Name: <SC>L</SC>-Serine
Brand: SIGMA

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, USP testing specifications

Synonym(s):

L Serine, (S)-2-Amino-3-hydroxypropionic acid

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About This Item

Linear Formula:

HOCH₂CH(NH₂)CO₂H

CAS Number:

56-45-1

Molecular Weight:

105.09

NACRES:

NA.26

PubChem Substance ID:

24899599

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

200-274-3

MDL number:

MFCD00064224

Beilstein/REAXYS Number:

1721404

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Properties

Product Name

L-Serine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

biological source

non-animal source

Quality Level

300

agency

USP/NF, meets EP testing specifications, meets USP testing specifications

assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

222 °C (dec.) (lit.)

solubility

H₂O: 50 mg/mL

application(s)

pharmaceutical (small molecule)

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

Description

Application

L-Serine has been used as a supplement in a medium to culture Chinese hamster ovary TF 70R cell line and in mouse embryonic fibroblast (MEF)-media.

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.

Precursor of glycine by serine hydroxymethyltransferase.

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Abel Lajtha, Simo S. Oja, Pirjo Saransaari, Arne Schousboe

Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System (2007)

Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria

Taru Hilander

Nucleic Acids Research (2018)

Simultaneous environmental manipulations in semi-perfusion cultures of CHO cells producing rh-tPA

Biotechnology (2012)

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Global Trade Item Number

SKU	GTIN
S4311-100G	04061836925857
S4311-25G	04061836925918
S4311-1KG	04061836925895