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S7896

Syringaldazine

Name: Syringaldazine
Brand: SIGMA

indicator for laccase and peroxidase activity, ≥98% (TLC), powder or crystals

Synonym(s):

4-Hydroxy-3,5-dimethoxybenzaldehyde azine

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About This Item

Linear Formula:

[HOC₆H₂(OCH₃)₂CH=N-]₂

CAS Number:

14414-32-5

Molecular Weight:

360.36

NACRES:

NA.83

PubChem Substance ID:

24899766

UNSPSC Code:

12352204

EC Number:

238-390-1

MDL number:

MFCD00008363

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Properties

Product Name

Syringaldazine, indicator for laccase and peroxidase activity

Quality Level

100

assay

≥98% (TLC)

form

powder or crystals

mp

209-210 °C (lit.)

solubility

DMF: soluble, slightly hazy

storage temp.

2-8°C

SMILES string

COc1cc(\C=N\N=C\c2cc(OC)c(O)c(OC)c2)cc(OC)c1O

InChI

1S/C18H20N2O6/c1-23-13-5-11(6-14(24-2)17(13)21)9-19-20-10-12-7-15(25-3)18(22)16(8-12)26-4/h5-10,21-22H,1-4H3/b19-9+,20-10+

InChI key

YARKTHNUMGKMGS-LQGKIZFRSA-N

Description

Application

Syringaldazine has been used as a substrate to determine the enzymatic activity of the cuticular laccase.

Biochem/physiol Actions

Syringaldazine is a dimer of two molecules of 2,6-dimethoxyphenol linked by an azide bridge. It is a phenolic non-autooxidizable laccase-specific compound, that facilitates the detection of fungal laccase in some varieties of fungi. In addition, it also acts as an indicator for peroxidase activity in fungi.

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pictograms

GHS02

signalword

Warning

hcodes

H228

pcodes

P210

Hazard Classifications

Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Protocols

漆酶的酶学测定（EC 1.10.3.2）

漆酶（EC 1.10.3.2）是一种铜酶，可氧化各种类型的酚和类似的芳香族化合物芳香胺，并同时将分子氧还原为水，因此可被用作生物催化剂。

Enzymatic Assay: Laccase (EC 1.10.3.2)

Laccase, a biocatalyst, oxidizes aromatic compounds with molecular oxygen reduction, making it useful in various applications.

Quantitative estimation of laccase forms in some white-rot fungi using syringaldazine as a substrate

Leonowicz A and Grzywnowicz K

Enzyme and Microbial Technology, 3(1), 55-58 (1981)

Syringaldazine, an effective reagent for detecting laccase and peroxidase in fungi

Harkin JM and Obst JR

Experientia, 29(4), 381-387 (1973)

Aptitude of Oxidative Enzymes for Treatment of Wastewater Pollutants: A Laccase Perspective

Unuofin JO, et al.

Molecules (Basel), 24(11), 2064-2064 (2019)

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Global Trade Item Number

SKU	GTIN
S7896-1G	04061836960384
S7896-500MG	04061836960391