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S9012

Sulforhodamine B sodium salt

Powder

Synonym(s):

Acid red 52; Acid Rhodamine B

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About This Item

Empirical Formula (Hill Notation):
C27H29N2NaO7S2
CAS Number:
3520-42-1
Molecular Weight:
580.65
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24899824
EC Number:
222-529-8
MDL number:
MFCD00010180
Colour Index Number:
45100
Beilstein/REAXYS Number:
3886008
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Product Name

Sulforhodamine B sodium salt, Technical grade

Quality Level

200

form

powder

composition

Dye content, ~75%

εmax

≥85000 at 554-560 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S([O-])(=O)=O)=[N+](\CC)CC)c1

InChI

1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1

InChI key

SXQCTESRRZBPHJ-UHFFFAOYSA-M

General description

Sulforhodamine B (also known as SRB, kiton rhodamine B, lissamine rhodamine B, or sulphorhodamine B) is a bright-pink anionic, aminoxanthene dye carrying two sulfonate substituents.

Application

Sulforhodamine B (SRB) is known for use in SRB assay for the determination of in vitro cytotoxicity through staining and the observation of live cells, proliferation and drug screening.

It has been used in the SRB assay to evaluate the effect of mouthwashes on protein content in primary cultures of human fibroblasts.

It is also suitable as a microscopic tracer for the assessment of blood-brain barrier integrity by post mortem inspection of frozen sections. SRB is useful as a caries detector dye with subsequent inspection of histological material.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SHBL1004
MKCF2845
MKBX6262V
MKBT0470V
MKBQ6027V

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M Maltz et al.
Journal of dentistry, 40(9), 776-782 (2012-06-06)
The aim of this study was to compare microbiological infection after conventional carious dentine removal with incomplete carious dentine removal and sealing. Eighty-seven patients (12-50 years of age) under treatment at the Dental Clinics of the Federal University of Rio
Xinyuan Chen et al.
Journal of controlled release : official journal of the Controlled Release Society, 159(1), 43-51 (2012-01-21)
Full-surface laser ablation has been shown to efficiently disrupt stratum corneum and facilitate transcutaneous drug delivery, but it is frequently associated with skin damage that hampers its clinic use. We show here that a safer ablative fractional laser (AFL) can
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Global Trade Item Number

SKUGTIN
S9012-25G04061836961183
S9012-1G04061824379457
S9012-5G04061836961190