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Merck
CN

S9637

Sodium succinate dibasic hexahydrate

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym(s):

Butanedioic acid disodium salt, Succinic acid disodium salt

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About This Item

Linear Formula:
NaOOCCH2CH2COONa · 6H2O
CAS Number:
Molecular Weight:
270.14
UNSPSC Code:
12352207
NACRES:
NA.71
PubChem Substance ID:
EC Number:
205-778-7
Beilstein/REAXYS Number:
3921044
MDL number:
Solubility:
H2O: 100 mg/mL, clear, colorless
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product line

BioReagent

Quality Level

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

pH

8—9.5 (25 °C, 270 g/L)

solubility

H2O: 100 mg/mL, clear, colorless

SMILES string

O.O.O.O.O.O.[Na+].[Na+].[O-]C(=O)CCC([O-])=O

InChI

1S/C4H6O4.2Na.6H2O/c5-3(6)1-2-4(7)8;;;;;;;;/h1-2H2,(H,5,6)(H,7,8);;;6*1H2/q;2*+1;;;;;;/p-2

InChI key

ZBTUYCUNQBRXOR-UHFFFAOYSA-L

General description

Sodium succinate dibasic hexahydrate is the sodium salt of succinic acid, a dicarboxylic acid. This versatile compound finds extensive use in cell biology, cell culture, and biochemical research applications. It serves as both an energy source and a buffer in cell culture and cell biology research, particularly within the Tricarboxylic Acid (TCA) or Krebs cycle. It is hypothesized that Sodium succinate dibasic hexahydrate acts as an ionophore, facilitating the transport of ions across cell membranes and thus influencing cellular metabolism. Also known as Succinic acid disodium salt, this product provides the necessary substrate for ATP (adenosine triphosphate) production, essential for optimal cellular function.

Application

Sodium succinate dibasic hexahydrate has been used:
  • as a supplement in the assay medium to incubate mitochondria to measure the specific activity of complex-II
  • as a component in plant induction medium/ protoplast induction media (PIM) for plant regeneration
  • as a small-molecule additive in the fresh medium to study its positive synergistic effects on transgene expression in Chinese hamster ovary (CHO) cells

Features and Benefits

  • Versatile and adaptable for a wide variety of laboratory and research applications
  • BioReagent Grade Sodium succinate for your Cell Biology and Biochemical research
  • Tested for Mammalian and Insect cell culture applications

Other Notes

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Global Trade Item Number

SKUGTIN
S9637-500G04061836961602
S9637-100G04061836961596
S9637-1KG04061835149087