Anti-HSP90AB1 (Ab-254) antibody produced in rabbit

HSP90AB1 (heat shock protein 90 αfamily class B member 1) belongs to the Hsp90 family. It consists of major members-Hsp90α, Hsp90β, GRP94 (glucose-regulated protein 94) and Hsp75. It is located on chromosome 6p21. It is an ATP-dependent molecular chaperone, that is of 90kDa.

Molecular chaperone. Has ATPase activity.

Peptide sequence around aa. 252-256 (V-G-S-D-E), according to the protein HSP90AB1.

HSP90AB1 (heat shock protein 90 αfamily class B member 1) participates in signal transduction, protein folding and degradation, and morphological evolution. It is required for the transport of client proteins between the cytoplasm and nucleus. In lung adenocarcinoma patients, overexpression of HSP90AB1 in non-small cell lung cancer tissues results in imperfect clinical predictions. Suppression of this gene reduces the potential of endothelial cells to form tube structures.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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