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Merck
CN

SAB4300571

Anti-MAP1LC3A antibody

rabbit polyclonal

Synonym(s):

Anti-LC3 antibody produced in rabbit, Anti-LC3A antibody produced in rabbit, Anti-MAP1ALC3 antibody produced in rabbit, Anti-MAP1BLC3 antibody produced in rabbit, Anti-microtubule-associated protein 1 light chain 3 alpha antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, WB
Citations:
14
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Product Name

Anti-MAP1LC3A antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~16 kDa, ~18 kDa

species reactivity

rat, human, mouse

concentration

1 mg/mL

technique(s)

indirect immunofluorescence: 1:100-1:200, western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(R-P-F-K-Q)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAP1LC3A(84557)

General description

Probably involved in formation of autophagosomal vacuoles (autophagosomes).

Immunogen

Peptide sequence around aa. 5-10 (R-P-F-K-Q), according to the protein MAP1LC3A.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Antonio Piras et al.
Cell death & disease, 8(12), 3223-3223 (2017-12-21)
Spinal muscular atrophy (SMA) is a recessive autosomal neuromuscular disease, due to homozygous mutations or deletions in the telomeric survival motoneuron gene 1 (SMN1). SMA is characterized by motor impairment, muscle atrophy, and premature death following motor neuron (MN) degeneration.
Conghong Shi et al.
Biochemical and biophysical research communications, 452(3), 308-314 (2014-08-15)
Recent research has revealed a role for Ambra1, an autophagy-related gene-related (ATG) protein, in the autophagic pro-survival response, and Ambra1 has been shown to regulate Beclin1 and Beclin1-dependent autophagy in embryonic stem cells and cancer cells. However, whether Ambra1 plays
Tangli Xiao et al.
Molecular and cellular biochemistry, 394(1-2), 145-154 (2014-05-23)
The aim was to explore the effects of rapamycin on autophagy and injury of podocytes in streptozocin (STZ)-induced type 1 diabetic mice, and its role in delaying progression of diabetic nephropathy. In this study, male Balb/c mice were divided into



Global Trade Item Number

SKUGTIN
SAB4300571-100UG04061832704944