Anti-Glial Fibrillary Acidic Protein Antibody

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

Glial fibrillary acidic protein (GFAP) is an intermediate-filament protein found in the astrocytes of CNS (central nervous system).{56,59} It is located on chromosome 17q21.

The antibody detects endogenous level of total GFAP protein.

Peptide sequence around aa. 423-427 (E-S-K-Q-E), according to the protein NP_002046.1

Glial fibrillary acidic protein (GFAP) regulates intermediate filament network dynamics, cell morphology and focal adhesions. It helps in maintaining myelination and stability of CNS (central nervous system) white matter architecture.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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