SAB4500423
Anti-ADORA2A antibody produced in rabbit
affinity isolated antibody
Synonym(s):
ADORA2, ADORA2A, Adenosine receptor A2a
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Citations:
5
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 44 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ADORA2A(135)
General description
Anti-ADORA2A Antibody detects endogenous levels of total ADORA2A protein.
Adenosine A2a receptor (ADORA2A) is a G protein-coupled receptor. It is highly expressed in the brain. It is located on human chromosome 22q11.23.
Immunogen
The antiserum was produced against synthesized peptide derived from human ADORA2A.
Immunogen Range: 321-370
Immunogen Range: 321-370
Biochem/physiol Actions
Activation of the adenosine A2a receptor (ADORA2A) prevents T-cell proliferation and production of pro-inflammatory cytokines. It functions in increasing cytosolic cAMP levels. The protein has been associated with stimulation of liver ischemic preconditioning. ADORA2A is also linked to dermal fibrosis and scleroderma.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Pharmacological Preconditioning by Adenosine A2a Receptor Stimulation: Features of the Protected Liver Cell Phenotype
Alchera E, et al.
BioMed Research International (2015)
Adenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balance
Perez-Aso M, et al.
Purinergic Signaling, 9(4), 573-583 (2013)
A genetic variation in the ADORA2A gene modifies age at onset in Huntington's disease
Dhaenens CM, et al.
Neurobiology of Disease, 35(3), 474-476 (2009)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4500423-100UG | 04061835711239 |