SAB5200106
Anti-SCNN1B antibody produced in rabbit
1 mg/mL, affinity isolated antibody
Synonym(s):
Anti-ENaC Beta, Anti-Scnn1b
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, IP, WB
Citations:
4
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 87 kDa
species reactivity
mouse, human, rat
concentration
1 mg/mL
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Scnn1b(24767)
General description
Sodium channel epithelial 1 β subunit (SCNN1B) is expressed in the posterior cerebral artery of rats. It is one of the subunits of epithelial sodium channels. The gene ID of the protein is 24767.
Immunogen
AA617–638 of the rat sequence
Biochem/physiol Actions
Detects ~87 kDa.
Sodium channel epithelial 1 β subunit (SCNN1B) is involved in sodium transport in the epithelium.
Features and Benefits
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Physical form
PBS, 50% glycerol, and 0.09% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
低风险生物材料
常规特殊物品
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Chengbiao Zhang et al.
American journal of physiology. Renal physiology, 312(4), F682-F688 (2017-04-04)
Mice transgenic for genomic segments harboring PHAII (pseudohypoaldosteronism type II) mutant Wnk4 (with-No-Lysine kinase 4) (TgWnk4PHAII) have hyperkalemia which is currently believed to be the result of high activity of Na-Cl cotransporter (NCC). This leads to decreasing Na+ delivery to
Lijun Wang et al.
Journal of the American Society of Nephrology : JASN, 26(11), 2678-2690 (2015-04-08)
Kcnj10 encodes the inwardly rectifying K(+) channel Kir4.1 in the basolateral membrane of the distal convoluted tubule (DCT) and is activated by c-Src. However, the regulation and function of this K(+) channel are incompletely characterized. Here, patch-clamp experiments in Kcnj10-transfected
Eok-Cheon Kim et al.
Experimental physiology, 97(4), 544-555 (2011-11-18)
It has been suggested that mechanosensitive ion channels initiate myogenic responses in vessels; however, the molecular identity of the mechanosensitive ion channel complex is unknown. Although previous reports have suggested that epithelial Na(+) channel (ENaC) proteins are mechanotransducers in arteries
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB5200106-100UG | 04061838059123 |