SAB5200112
Anti-Aquaporin-4 Antibody
rabbit polyclonal
Synonym(s):
Anti-AQP4, Anti-Aquaporin 4
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, WB
Citations:
4
Product Name
Anti-AQP4 antibody produced in rabbit, 1 mg/mL, affinity isolated antibody
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 35 kDa
species reactivity
rat, human, mouse
concentration
1 mg/mL
technique(s)
indirect immunofluorescence: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Aqp4(25293)
General description
Aquaporin 4 (AQP4) is expressed in the nervous system. The gene ID of the protein is 25293.
Immunogen
C-terminal peptide
Biochem/physiol Actions
Aquaporin 4 (AQP4) functions as a water channel in the rat brain.
Detects ~35 kDa. May detect larger glycosylated bands ~50 kDa.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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S Ceccariglia et al.
Neuroscience, 274, 273-288 (2014-06-10)
Trimethyltin chloride (TMT) is a neurotoxicant producing neuronal degeneration and reactive astrogliosis in the mammalian central nervous system, especially the hippocampus. A previous magnetic resonance imaging investigation in TMT-treated rats evidenced dilation of lateral ventricles, also suggesting alterations in blood-brain
Alex J Smith et al.
Acta neuropathologica communications, 7(1), 74-74 (2019-05-10)
Redistribution of the water channel aquaporin-4 (AQP4) away from astrocyte endfeet and into parenchymal processes is a striking histological feature in mouse models of Alzheimer's disease (AD) and other neurological conditions with prominent astrogliosis. AQP4 redistribution has been proposed to
Gökhan Akdemir et al.
Neuroscience letters, 574, 70-75 (2014-04-11)
Astrocyte water channel aquaporin-4 (AQP4) facilitates water movement across the blood-brain barrier and into injured astrocytes. We previously showed reduced cytotoxic brain edema with improved neurological outcome in AQP4 knockout mice in water intoxication, infection and cerebral ischemia. Here, we
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB5200112-100UL | 04061838059185 |