SAB5500001
Anti-β-Actin (ACTB) Antibody
rabbit monoclonal, SP124
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
SP124, monoclonal
Application:
FACS, IHC
Citations:
29
Product Name
Anti-beta-Actin antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP124, affinity isolated antibody
biological source
rabbit
Quality Level
recombinant
expressed in proprietary host
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
SP124, monoclonal
species reactivity
human (tested)
species reactivity (predicted by homology)
chicken, mouse, rat, bovine, rabbit, pig, dog, hamster, frog
technique(s)
flow cytometry: 1:100, immunoblotting: 1:200, immunohistochemistry: 1:200
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... ACTB(60)
General description
ACTB (actin β) gene codes for β-actin. It is a cytoskeletal housekeeping protein. It is present in the cytoplasm. This gene is located on human chromosome 7p22.1.
Beta-actin is a nonmuscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. Antibody to beta-actin provides a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.
Immunogen
Synthetic peptide near the N-terminus of human beta-Actin protein.
Application
Anti-Actin-Beta antibody has been used in western blotting.
Biochem/physiol Actions
β-Actin modulates cell growth, migration and the G-actin pool. Mutations in ACTB leads to pleiotropic developmental disorder.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
Regulatory Information
低风险生物材料
常规特殊物品
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Lin Liao et al.
Experimental cell research, 359(1), 266-274 (2017-07-22)
We have established that annexin A2 (ANXA2) is an important factor in the experimental hepatopulmonary syndrome (HPS) serum-induced proliferation of pulmonary arterial smooth muscle cells (PASMCs). However, the detailed mechanism remains unclear. ANXA2 translocated to the caveolin-enriched microdomains (caveolae) in
Jin-Xing Lv et al.
Molecular medicine reports, 19(1), 271-279 (2018-11-16)
The aim of the present study was to investigate the underlying mechanisms of hypoxia‑induced microRNA (miR)‑210 effects on mouse GC‑2spd (GC‑2) cells. GC‑2 cells were subjected to hypoxia or normoxia for 12, 24, 48 and 72 h. Apoptosis of GC‑2 cells
DEK: A novel early screening and prognostic marker for breast cancer
Ying G and Wu Y
Molecular Medicine Reports, 12(5), 7491-7495 (2015)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB5500001-100UL | 04061837832826 |