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Merck
CN

SAB5701723

Anti-Phospho-AKT2-S474 antibody produced in rabbit

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, mouse
Application:
IHC, WB
Citations:
-
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biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human, mouse

concentration

0.59 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer474)

Gene Information

human ... AKT2(208)

General description

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Immunogen

A synthetic phosphorylated peptide around S474 of human AKT2 (NP_001617.1).

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
低风险生物材料

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Global Trade Item Number

SKUGTIN
SAB5701723-100UL04065267674971