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SAB5701754

Anti-Phospho-HDAC5-S498 antibody produced in rabbit

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
IHC, WB
Citations:
-
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biological source

rabbit

Quality Level

100

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human, rat, mouse

concentration

1.09 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

UniProt accession no.

Q9UQL6

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer498)

Gene Information

human ... HDAC5(10014)

General description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding S498 of human HDAC5

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number
21153610301

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Global Trade Item Number

SKUGTIN
SAB5701754-100UL04065267675282