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Merck
CN

SAB5702076

Anti-TLR7 Antibody, clone 3G6S4, Rabbit Monoclonal

Synonym(s):

TLR7,TLR7-like

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
3G6S4, monoclonal
Application:
WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

3G6S4, monoclonal

form

liquid

mol wt

140 kDa

species reactivity

human

concentration

0.85 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

SKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVAYSQVFKETV

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TLR7(51284)

General description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 950-1049 of human TLR7 (Q9NYK1).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB


Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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Global Trade Item Number

SKUGTIN
SAB5702076-100UL04065270652997