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Merck
CN

SML2088

Procainamide hydrochloride

≥98% (HPLC), powder, sodium channel blocker

Synonym(s):

Procainamide hydrochloride, 4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride, 4-Aminobenzoic acid 2-diethylaminoethylamide, Amidoprocaine, Amisalin, Cardiorytmin, HC 5006, Novocaine amide hydrochloride, Novocamid hydrochloride, Procainamide monohydrochloride, Procamid, Procamide, Procan SR, Procapan, Procardyl, Pronestyl, Pronestyl hydrochloride, Spicain amide

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About This Item

Linear Formula:
H2NC6H4CONHCH2CH2N(C2H5)2·HCl
CAS Number:
Molecular Weight:
271.79
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
210-381-7
Beilstein/REAXYS Number:
3729517
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Product Name

Procainamide hydrochloride, ≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

mp

167-169 °C (lit.)

solubility

H2O: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

Cl.CCN(CC)CCNC(=O)c1ccc(N)cc1

InChI

1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H

InChI key

ABTXGJFUQRCPNH-UHFFFAOYSA-N

Application

Procainamide hydrochloride (PAH) is suitable to investigate its binding behavior with human serum albumin and bovine serum albumin by fluorescence quenching study to understand the pharmacokinetic and pharmacodynamic mechanisms of PAH.

Biochem/physiol Actions

Procainamide hydrochloride is a sodium channel blocker and Class IA anti-arrhythmic. It has also been shown to Inhibit DNA methyltransferase and modulate epigenetic regulation of gene expression.


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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3



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Articles

This application note describes the released N-Glycan analysis of a monoclonal antibody, cetuximab, labeled with procainamide, using a BIOshell™ Glycan HPLC column.





Global Trade Item Number

SKUGTIN
SML2088-1G04061835371839
SML2088-250MG04061835371884