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Merck
CN

SRE0049

Lipase from porcine pancreas

Suitable for manufacturing of diagnostic kits and reagents, ≥20,000 units/mg protein, lyophilized powder

Synonym(s):

PPL, Triacylglycerol acylhydrolase, Triacylglycerol lipase

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About This Item

CAS Number:
EC Number:
232-619-9
UNSPSC Code:
12352204
EC Number:
MDL number:
Specific activity:
≥20,000 units/mg protein
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Quality Level

form

lyophilized powder

specific activity

≥20,000 units/mg protein

composition

Protein, 40-70% biuret

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,16H,(H,12,14);/q;+1/b13-9-;

InChI key

QWZUIMCIEOCSJF-CHHCPSLASA-N

Application

Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel.

Biochem/physiol Actions

Lipase is a hydrolytic enzyme produced by various tissues. This enzyme catalyzes the hydrolysis of triacylglycerols to yield glycerol and free fatty acids, which is a rate-limiting for the exclusion of lipoprotein triglycerides from the circulation. It is associated with certain metabolic diseases, including obesity and familial combined hyperlipidemia.
Lipases catalyze the hydrolysis of esters in aqueous solutions and the synthesis of esters in non-aqueous solutions. They also produce hydroxyl and carboxylic groups through the hydrolysis of ester linkages in poly(ethylene terephthalate).

Lipases catalyze the hydrolysis of triacylglycerols into glycerol and free fatty acids.

Other Notes

One unit will hydrolyze 1.0 microequivalent of fatty acid from a triglyceride in 1 hr at pH 7.7 at 37 °C using olive oil.


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

低风险生物材料

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8th International Symposium on Atherosclerosis., 265-267 (1989)
Lipoprotein lipase.
Eckel R H
The New England Journal of Medicine, 320(16), 1060-1068 (1989)



Global Trade Item Number

SKUGTIN
SRE0049-100KU04061837108976
SRE0049-1MU04061826704073