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Merck
CN

T3376

DL-α-Tocopherol acetate

≥96% (HPLC)

Synonym(s):

Vitamin E acetate, all-rac-α-Tocopheryl acetate

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About This Item

Empirical Formula (Hill Notation):
C31H52O3
CAS Number:
Molecular Weight:
472.74
UNSPSC Code:
12352205
NACRES:
NA.79
PubChem Substance ID:
EC Number:
231-710-0
Beilstein/REAXYS Number:
97512
MDL number:
Technical Service
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Quality Level

biological source

synthetic (organic)

assay

≥96% (HPLC)

form

viscous liquid

technique(s)

HPLC: suitable

color

colorless to dark yellow

density

0.96 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

General description

α-Tocopherol is a predominant form of vitamin E in human and animal tissues and also in leaf chloroplasts. It is the major form in supplements. DL-α-Tocopherol acetate is considered as the only storage form of vitamin E.

Application

DL-α-Tocopherol acetate has been used to study it effect on blood pressure and lipidic profile in streptozotocin-induced diabetes mellitus rats. It has also been used as a standard in α-tocopherol analysis using plasma sample and mature fresh tobacco leaves.

Biochem/physiol Actions

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves



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Articles

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.


High levels of dietary unsaturated fat decrease alpha-tocopherol content of whole body, liver, and plasma of chickens without variations in intestinal apparent absorption
Villaverde C, et al.
Poultry Science, 87(3), 497-505 (2008)
Nutrient Requirements of Fish and Shrimp (2011)
Rachel M Taylor et al.
PloS one, 11(3), e0151665-e0151665 (2016-03-24)
The current National Research Council (NRC) selenium (Se) requirement for the turkey is 0.2 μg Se/g diet. The sequencing of the turkey selenoproteome offers additional molecular biomarkers for assessment of Se status. To determine dietary Se requirements using selenoprotein transcript



Global Trade Item Number

SKUGTIN
T3376-5G04061835549993
T3376-100G04061835549986
T3376-25G04061835522620