Skip to Content
Merck
CN

Key Documents

View All Documentation

T3516

Thioflavin T

Powder

Synonym(s):

Basic Yellow 1, Thioflavine T

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C17H19ClN2S
CAS Number:
2390-54-7
Molecular Weight:
318.86
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24900146
EC Number:
219-228-9
MDL number:
MFCD00011944
Beilstein/REAXYS Number:
3922452
Colour Index Number:
49005
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Thioflavin T, used as stain for amyloid

Quality Level

200

form

powder

composition

Dye content, ≥65%

solubility

methanol: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Cl-].CN(C)c1ccc(cc1)-c2sc3cc(C)ccc3[n+]2C

InChI

1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1

InChI key

JADVWWSKYZXRGX-UHFFFAOYSA-M

General description

Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.

Application

Thioflavin T has been used to identify the presence of amyloid fibrils in samples.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Still not finding the right product?

Explore all of our products under Thioflavin T

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SHBN0977
SHBM5341
SHBL5339
SHBL4963
MKCF7876

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Matthew Biancalana et al.
Biochimica et biophysica acta, 1804(7), 1405-1412 (2010-04-20)
Intense efforts to detect, diagnose, and analyze the kinetic and structural properties of amyloid fibrils have generated a powerful toolkit of amyloid-specific molecular probes. Since its first description in 1959, the fluorescent dye Thioflavin-T (ThT) has become among the most
Jian Xiong et al.
Biophysical chemistry, 220, 42-48 (2016-11-20)
The hydrophobic fragment of the Alzheimer's related β-amyloid (Aβ) peptide, Aβ(25-40), aggregates and forms insoluble amyloid fibrils at a rate similar to the full-length peptide. In order to gain insight into the fibrillization of Aβ(25-40) and the ability of the
Pai Peng et al.
Nucleic acids research, 45(2), 541-546 (2016-12-03)
We present a conceptually new reversible nanosensor regulated by a DNA nanoswitch. This system is not only responsive to external stimuli (e.g. ATP) but also can be reversibly switched between 'OFF' and 'ON' states via toehold mediated strand displacement reactions.
View All Related Papers

Global Trade Item Number

SKUGTIN
T3516-25G04061837344510
T3516-5G04061837344527