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T6817

Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in mouse

Name: Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in mouse
Brand: SIGMA

clone 28401, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-TNF-α

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00162116

Conjugate:

unconjugated

Clone:

28401, monoclonal

Application:

ELISA (c), ICC, Neutral, WB

Citations:

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Properties

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

28401, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

capture ELISA: 4 μg/mL, neutralization: suitable, western blot: 1.0-2.0 μg/mL, immunocytochemistry: 8-25 μg/mL using Immersion fixed human peripheral blood mononuclear cells (PBMSs) stimulated with LPS and monensin.

impurities

<0.10 EU/μg

isotype

IgG1

UniProt accession no.

P01375

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TNF(7124)

Description

Immunogen

recombinant human TNF-α, expressed in E. coli

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.

Preparation Note

Purified using protein G

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

低风险生物材料

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IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease.

Fiorella Calabrese et al.

American journal of respiratory and critical care medicine, 178(9), 894-901 (2008-08-16)

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder of the lung, yet the mechanisms that regulate this immune-inflammatory response are not fully understood. We investigated whether IL-32, a newly discovered cytokine, was related to markers of inflammation and

CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients.

Rosario García-Vicuña et al.

Arthritis and rheumatism, 50(12), 3866-3877 (2004-12-14)

To explore the potential involvement of the chemokine system in synoviocyte-mediated tissue destruction in rheumatoid arthritis (RA), we studied the expression profile of chemokine receptors and their function in the migration, proliferation, and matrix metalloproteinase (MMP) production of cultured fibroblast-like

The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death.

C A Smith et al.

Cell, 76(6), 959-962 (1994-03-25)

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Global Trade Item Number

SKU	GTIN
T6817-500UG	04061832717463