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T8566

L-Tyrosine

Name: <SC>L</SC>-Tyrosine
Brand: SIGMA

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

Synonym(s):

(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine

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About This Item

Linear Formula:

4-(HO)C₆H₄CH₂CH(NH₂)CO₂H

CAS Number:

60-18-4

Molecular Weight:

181.19

PubChem Substance ID:

24900543

eCl@ss:

32160406

UNSPSC Code:

12352209

NACRES:

NA.26

EC Number:

200-460-4

MDL number:

MFCD00002606

Beilstein/REAXYS Number:

392441

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Properties

Product Name

L-Tyrosine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 99.0-101.0%

biological source

non-animal source

Quality Level

300

agency

USP/NF, meets EP testing specifications, meets USP testing specifications

product line

BioXtra

assay

99.0-101.0%

form

powder

optical activity

[α]25/D 11.2 to 9.8°, c = 5 in 1 M HCl (Specific Rotation 6.1 - 7.8 °)

shelf life

limited shelf life, expiry date on the label

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to off-white

mp

>300 °C (dec.) (lit.)

solubility

1 M HCl: 25 mg/mL

cation traces

Fe: ≤10 ppm, NH₄⁺: ≤0.02%

application(s)

advanced drug delivery
pharmaceutical (small molecule)

functional group

(phenol)

storage temp.

room temp

SMILES string

N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

InChI key

OUYCCCASQSFEME-QMMMGPOBSA-N

Description

General description

L-Tyrosine, an essential amino acid, plays a vital role in biochemical and cell culture research. In biochemical studies, L-Tyrosine is significant as a precursor to neurotransmitters like dopamine, norepinephrine, and epinephrine, which influence cellular communication and play a role in mood, attention, and energy levels. It also contributes to the synthesis of thyroid hormones, regulating metabolic processes. L-Tyrosine is employed to support cell growth and protein synthesis, facilitating experiments on cell maintenance and repair, making it a valuable tool in biochemical and cell culture investigations.

Application

L-Tyrosine has been used as a supplement in Dulbecco′s modified Eagle′s medium for culturing SY5Y neuroblastoma cells for stable isotope labeling of amino acids on cell culture (SILAC).

Biochem/physiol Actions

L-Tyrosine consists of a polar side chain and is a non-essential amino acid. It is utilized by cells to synthesize proteins that are involved in signal transduction. L-Tyrosine acts as a receiver of phosphate groups that are transferred by kinases.

Features and Benefits

Suitable for Cell Culture and Biochemical research
High-quality compound suitable for multiple research applications

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Amino acid precursor of dopamine and other catecholamines

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ppe

dust mask type N95 (US), Eyeshields, Gloves

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

11 - Combustible Solids

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Articles

L-Tyrosine in Cell Culture

Learn more about the amino acid L-Tyrosine and explore how it is used in cell culture media like MEM, DMEM, and RPMI. We offer a comprehensive portfolio of amino acid cell culture supplements and reagents.

Global Trade Item Number

SKU	GTIN
T8566-100G	04061837379345
T8566-1KG	04061837379369
T8566-10MG	04061837379352
T8566-25G	04061835514311