Key Documents

View All Documentation

U0881

Uric acid

Name: Uric acid
Brand: SIGMA

BioXtra, ≥99% (HPLC)

Synonym(s):

2,6,8-Trihydroxypurine

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₅H₄N₄O₃

CAS Number:

69-93-2

Molecular Weight:

168.11

UNSPSC Code:

12352005

NACRES:

NA.55

PubChem Substance ID:

24900620

EC Number:

200-720-7

Beilstein/REAXYS Number:

156158

MDL number:

MFCD00005712

Assay:

≥99% (HPLC)

Biological source:

animal (seabird feces (guano))

Form:

powder

Solubility:

1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

animal (seabird feces (guano))

Quality Level

200

product line

BioXtra

assay

≥99% (HPLC)

form

powder

impurities

≤0.005% Phosphorus (P)

ign. residue

≤0.1%

mp

>300 °C (lit.)

solubility

1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

cation traces

Al: ≤0.005%, Ca: ≤0.01%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.05%, Mg: ≤0.001%, NH₄⁺: ≤0.05%, Na: ≤0.1%, Pb: ≤0.001%, Zn: ≤0.0005%

SMILES string

O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)

InChI key

LEHOTFFKMJEONL-UHFFFAOYSA-N

Description

General description

Uric acid is the terminal product of purine degradation in humans. It is formed from the action of xanthine oxidase upon xanthine. Elevated levels of uric acid may clinically be manifested as gout. In species other than humans, uric acid can be further metabolized. In mammals other than primates, uric acid is converted to allantoin. In teleost fish, allantoin is further converted to allantoate, which is hydrolyzed to urea and glyoxylate. Uric acid may also be used in the biosynthesis of purines. It has been studied as a scavenger of biological free radicals like peroxynitrite. High-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) methods for uric acid have been published. Uric acid promotes monocyte chemoattractant protein-1 (MCP-1) expression in vascular smooth muscle cells.

Application

Uric acid has been used:

to prepare monosodium urate (MSU) crystals to study its effect on nuclear localization leucine-rich-repeat protein 1 (NLRP1) gene expression
as a reductant to test its protective potential against met-myoglobin formation
to prepare MSU to study its use as specific ligand of Clec12a.

Still not finding the right product?

Explore all of our products under Uric acid

ppe

Eyeshields, Gloves, type N95 (US)

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Uric Acid in Cell Culture

Uric acid present in animal sera impacts serum-supplemented classical cell culture systems, influencing cell culture performance.

Global Trade Item Number

SKU	GTIN
U0881-100G	04061837403866
U0881-10G	04061837403873
U0881-25G	04061837403880