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About This Item
Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
UNSPSC Code:
12352111
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-315-5
Beilstein/REAXYS Number:
635724
MDL number:
Assay:
98.0-102.0%
Quality Level
agency
USP/NF, meets USP testing specifications
assay
98.0-102.0%
form
solid
dilution
(for analytical testing)
mp
132-135 °C (lit.)
solubility
H2O: soluble 480 g/L at 20 °C
density
1.335 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
SMILES string
NC(N)=O
InChI
1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChI key
XSQUKJJJFZCRTK-UHFFFAOYSA-N
Gene Information
human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)
Application
Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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G L French et al.
Lancet (London, England), 2(8551), 117-119 (1987-07-18)
Tuberculostearic acid, a structural component of Mycobacterium tuberculosis, was identified by gas chromatography/mass spectrometry with selected ion monitoring in cerebrospinal fluid (CSF) from 13 patients with proven and 8 out of 9 patients with suspected tuberculous meningitis; the negative result
Annette Bahlinger et al.
Angewandte Chemie (International ed. in English), 53(33), 8779-8783 (2014-03-20)
β-Amino thioesters are important natural building blocks for the synthesis of numerous bioactive molecules. An organocatalyzed Mannich reaction was developed which provides direct and highly stereoselective access to acyclic β(2)- and β(2,3,3)-amino thioesters with adjacent tertiary and quaternary stereocenters. Mechanistic
Marco Benevento et al.
Nature communications, 5, 5613-5613 (2014-12-11)
The ectopic expression of Oct4, Klf4, c-Myc and Sox2 (OKMS) transcription factors allows reprogramming of somatic cells into induced pluripotent stem cells (iPSCs). The reprogramming process, which involves a complex network of molecular events, is not yet fully characterized. Here
Global Trade Item Number
| SKU | GTIN |
|---|---|
| U4884-100G | 04061837409677 |
| U4884-1KG | 04061826759318 |
| U4884-500G | 04061837409684 |
| U4884-5KG | 04061837409691 |