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WH0005530M3

Monoclonal Anti-PPP3CA antibody produced in mouse

clone 2G8, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-CALN, Anti-CALNA, Anti-CALNA1, Anti-CCN1, Anti-CNA1, Anti-PPP2B, Anti-protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00282168
Conjugate:
unconjugated
Clone:
2G8, monoclonal
Application:
ELISA (i), IF, WB
Citations:
1
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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2G8, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunofluorescence: suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

isotype

IgG2aκ

GenBank accession no.

NM_000944

UniProt accession no.

Q08209

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PPP3CA(5530)

Immunogen

PPP3CA (NP_000935, 1 a.a. ~ 84 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAP

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number
07145-2G8

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Liyun Luo et al.
Nature communications, 12(1), 2699-2699 (2021-05-13)
Resistance to Herceptin represents a significant challenge for successful treatment of HER2-positive breast cancer. Here, we show that in Herceptin-sensitive cells, FOXO3a regulates specific miRNAs to control IGF2 and IRS1 expression, retaining basic IGF2/IGF-1R/IRS1 signaling. The basic activity maintains expression

Global Trade Item Number

SKUGTIN
WH0005530M3-100UG04061829599904