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46958

Retinyl acetate

analytical standard

Synonym(s):

Retinol acetate, Vitamin A acetate

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About This Item

Empirical Formula (Hill Notation):
C22H32O2
CAS Number:
127-47-9
Molecular Weight:
328.49
EC Number:
204-844-2
UNSPSC Code:
12164500
PubChem Substance ID:
24870469
Beilstein/REAXYS Number:
1915439
MDL number:
MFCD00019413
NACRES:
NA.24
eCl@ss:
34058009
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grade

analytical standard

Quality Level

100

CofA

current certificate can be downloaded

feature

standard type fat soluble vitamin

packaging

ampule of 100 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

57-58 °C

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

-10 to -25°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

General description

Retinyl acetate is a naturally occurring long-chain fatty acid ester of retinol (Vitamin A). Retinyl acetate is suitable for use in the retention identification of the analyte when using HPLC and GC. Not intended for use as an activity reference standard.

Application

The analytical standard can also be used as follows:
  • Simultaneous determination of nine major fat-soluble vitamins― retinyl acetate, retinyl palmitate, retinol, α-tocopherol, α-tocopheryl acetate, cholecalciferol, ergocalciferol, phylloquinone, menaquinone in various commercial food product samples by supercritical fluid chromatography combined with mass spectrometric detection
  • Optimization of a supercritical fluid chromatographic method (SFC) for the simultaneous estimation of fat-soluble vitamins (FSVs) in hemp seed oil and waste fish oil samples, in combination with a diode array detector (DAD)
  • High-performance liquid chromatographic (HPLC) separation and quantification of β-carotene and vitamin A and E esters in infant formulae samples with fluorescence detection (FLD)
  • Analysis of cooking oil samples for the determination of fat-soluble vitamins and carotenoids using an ultra-performance convergence chromatography (UPC2) method
  • Multi-residue estimation of vitamin A and its derivatives in seven cosmetic product samples by liquid chromatography coupled with UV detection

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LC26462V
LC25803V
LC24632V
LC23763V
LC23096V

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Protocols

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

Emmanuel K Aklamati et al.
The Journal of nutrition, 140(9), 1588-1594 (2010-07-28)
A survey indicated that high-dose vitamin A (HD-VA) supplements had no apparent effect on vitamin A (VA) status, assessed by serum retinol concentrations, of Zambian children lt 5 y of age. To explore possible reasons for the lack of response
Z Wojnarowska et al.
Physical review. E, Statistical, nonlinear, and soft matter physics, 83(5 Pt 1), 051502-051502 (2011-07-07)
Vitamin-A acetate is one of the most versatile vitamins. It is applied in medicine because of its antioxidative properties, in tumor therapy because of its cytostatic activity, and in cosmetics because of its nutritional additives. Herein, using broadband dielectric spectroscopy
Natalia Cernicchiaro et al.
Foodborne pathogens and disease, 7(9), 1071-1081 (2010-05-27)
Alteration of the gastro-intestinal tract through manipulation of cattle diets has been proposed as a preharvest control measure to reduce fecal shedding of Escherichia coli O157:H7. The objective of this study was to examine the effects of the energy source's
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Global Trade Item Number

SKUGTIN
4695808012992469583