Isoxaben

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ. Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate. Download your certificate at: http://www.sigma aldrich.com

Isoxaben is a pre-emergence broad-leaf herbicide used primarily on small grains, turf, and ornamentals. This systematic herbicide is absorbed primarily by roots and translocated to stems and leaves. Isoxaben is a highly selective and potent inhibitor of cellulose biosynthesis in plants. It inhibits the incorporation of glucose into the cellulose-rich acid-insoluble fraction of isolated cell walls and disrupts its growth.

Isoxaben is approved for use in European Union (EU) according to Regulation (EC) No 1107/2009 (repealing Directive 91/414/EEC). As per Reg. (EC) No 149/2008, maximum residue levels (MRLs) have been set for various products of plant and animal origin from 0.01 to 0.1 mg/kg.

It is intended to be used as a certified reference material (CRM) for calibration in chromatography and other analytical techniques. Isoxaben CRM may also find its use as described below:

• To measure the effect of isoxaben on the incorporation of radiolabeled glucose, leucine, uracil, and acetate into acid-insoluble cell wall material, protein, nucleic acids, and fatty acids, respectively, in Arabidopsis thaliana
• To determine the relative toxicities of isoxaben and two of its primary metabolites in soybean and wheat cell cultures
• To investigate the effect of trifluralin, pronamide, haloxyfop-p methyl, propaquizafop, and isoxaben on weed control and oilseed rape yield
• To study the degradation of isoxaben in soil and an aqueous system followed by isolation and identification of degradation products formed
• To examine the effect of four different organic wastes, composted sheep manure, spent coffee grounds, composted pine bark, and coir, on potential groundwater pollution of propanil, isoxaben, cadusafos, and pencycuron under laboratory conditions

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TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany