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Merck
CN

1085003

USP

Caffeine

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1H-Purine-2,6-dione, 1,3,7-Trimethylxanthine

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About This Item

Empirical Formula (Hill Notation):
C8H10N4O2
CAS Number:
Molecular Weight:
194.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
17705
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grade

pharmaceutical primary standard

API family

pentoxifylline, caffeine, dimenhydrinate

manufacturer/tradename

USP

mp

234-236.5 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChI key

RYYVLZVUVIJVGH-UHFFFAOYSA-N

Gene Information

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Caffeine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Caffeine Citrate Injection
  • Caffeine Citrate Oral Solution
  • Acetaminophen and Caffeine Tablets
  • Ergotamine Tartrate and Caffeine Tablets
  • Butalbital, Aspirin, and Caffeine Capsules
  • Ergotamine Tartrate and Caffeine Suppositories

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


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Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

11 - Combustible Solids

Regulatory Information

监管及禁止进口产品

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Analysis of multicomponent formulations containing phenylpropanolamine hydrochloride, caffeine and diazepam by using LC
Pistos.C and Stewart.TJ
Journal of Pharmaceutical and Biomedical Analysis, 25, 493-499 (2001)
Quantitative reversed-phase high-performance liquid chromatographic analysis of ampicillin
Margosis M, et al.
Journal of Chromatography A, 236(2), 461-468 (1982)
Caffeine Citrate Oral Solution
United States Pharmacopeia, 30(5), 663-663 (2013)



Global Trade Item Number

SKUGTIN
1085003-200MG04061838686138