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1129007

USP

Chlortetracycline hydrochloride

Name: Chlortetracycline hydrochloride
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

7-Chlorotetracycline hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₂₃ClN₂O₈ · HCl

CAS Number:

64-72-2

Molecular Weight:

515.34

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329749348

MDL number:

MFCD00082440

Beilstein/REAXYS Number:

3858364

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Properties

grade

pharmaceutical primary standard

API family

chlortetracycline

form

solid

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

Cl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O

InChI

1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1

InChI key

CBHYYLPALVVVEY-LYNLVHCPSA-N

Description

General description

Chlortetracycline hydrochloride is a first-generation tetracycline antibiotic with activity against a wide spectrum of bacteria. It functions by preventing aminoacyl-tRNA attachment to the bacterial ribosome. The USP standard aids in identity verification and quantitative assay testing.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Chlortetracycline hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

Chlortetracycline Hydrochloride Ointment
Chlortetracycline Hydrochloride Tablets
Chlortetracycline Hydrochloride Soluble Powder
Chlortetracycline Hydrochloride Ophthalmic Ointment
Chlortetracycline and Sulfamethazine Bisulfates Soluble Powder
Chlortetracycline Bisulfate

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopeia.

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pictograms

GHS08,GHS07

signalword

Warning

hcodes

H315,H317,H319,H335,H361fd

pcodes

P202 - P261 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c