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About This Item
Empirical Formula (Hill Notation):
C22H29FO4
CAS Number:
Molecular Weight:
376.46
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
pharmaceutical primary standard
API family
fluorometholone
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14
InChI
1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
InChI key
FAOZLTXFLGPHNG-KNAQIMQKSA-N
Gene Information
human ... NR3C1(2908)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Fluorometholone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Fluorometholone Acetate
- Fluorometholone Ophthalmic Suspension
- Hydrocortisone Hemisuccinate
- Hydrocortisone Sodium Succinate for Injection
- Methylprednisolone Hemisuccinate
- Methylprednisolone Sodium Succinate for Injection
Biochem/physiol Actions
Clinically significant in allergic conjunctivitis and as anti-inflammatory following cataract surgery.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
涉药品监管产品
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Tear menisci after laser in situ keratomileusis with mechanical microkeratome and femtosecond laser.
Wenjia Xie et al.
Investigative ophthalmology & visual science, 55(9), 5806-5812 (2014-08-26)
To investigate the effect on tear menisci after laser in situ keratomileusis (LASIK) with flap creation by either microkeratome or femtosecond laser. Sixty eyes of 30 myopes were analyzed. Fifteen patients underwent LASIK with Moria II microkeratome, and the other
Hua Gao et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 252(6), 963-968 (2014-05-07)
To evaluate the feasibility of partial lamellar keratoplasty (LK) for treatment of peripheral corneal disease (PCD) using a graft from the corneoscleral rim preserved in glycerin. Patients who underwent LK for PCD at Shandong Eye Hospital from January 2006 to
Asimina Mataftsi et al.
The British journal of ophthalmology, 95(11), 1531-1533 (2011-02-08)
Although fluorometholone (FML) is considered a steroid of minimal ocular penetration, reports in children have shown dose-dependent intraocular pressure (IOP) rise. The authors aimed to assess whether reducing regimens of FML for paediatric ocular surface disease have sustained clinically significant
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 1278007-200MG | 04061838598349 |