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1357001

USP

L-Leucine

Name: <SC>L</SC>-Leucine
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(S)-2-Amino-4-methylpentanoic acid

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About This Item

Linear Formula:

(CH₃)₂CHCH₂CH(NH₂)CO₂H

CAS Number:

61-90-5

Molecular Weight:

131.17

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750237

MDL number:

MFCD00002617

Beilstein/REAXYS Number:

1721722

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Properties

grade

pharmaceutical primary standard

API family

leucine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

ʟ-Leucine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Leucine

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Cathepsin S activity controls ischemia-induced neovascularization in mice.

Xiang Li et al.

International journal of cardiology, 183, 198-208 (2015-02-11)

Evidence from human and animal studies has demonstrated elevated levels of the cysteine protease cathepsin S (CatS) in hypoxic atherosclerotic lesions. We hypothesized that silencing of CatS gene would suppress ischemia-induced angiogenic action. Left femoral artery ligation-induced ischemia in mice

Ghrelin inhibits the differentiation of T helper 17 cells through mTOR/STAT3 signaling pathway.

Yanhui Xu et al.

PloS one, 10(2), e0117081-e0117081 (2015-02-07)

Enhanced activity of interleukin 17 (IL-17) producing T helper 17 (Th17) cells plays an important role in autoimmune and inflammatory diseases. Significant loss of body weight and appetite is associated with chronic inflammation and immune activation, suggesting the cross talk

Effects of leucine supplementation and serum withdrawal on branched-chain amino acid pathway gene and protein expression in mouse adipocytes.

Abderrazak Kitsy et al.

PloS one, 9(7), e102615-e102615 (2014-07-23)

The essential branched-chain amino acids (BCAA), leucine, valine and isoleucine, are traditionally associated with skeletal muscle growth and maintenance, energy production, and generation of neurotransmitter and gluconeogenic precursors. Recent evidence from human and animal model studies has established an additional

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Global Trade Item Number

SKU	GTIN
1357001-200MG	04061838730947