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About This Item
Empirical Formula (Hill Notation):
C15H12I3NO4
CAS Number:
Molecular Weight:
650.97
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2710227
grade
pharmaceutical primary standard
API family
liothyronine
manufacturer/tradename
USP
mp
234-238 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O
InChI
1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
InChI key
AUYYCJSJGJYCDS-LBPRGKRZSA-N
Gene Information
human ... THRA(7067), THRB(7068)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Liothyronine USP reference standard for use in specified quality tests and assays.
Also used to prepare standard, standard stock, Liothyronine stock, and resolution solutions for assay, and identification test according to given below monographs of the United States Pharmacopeia (USP):
Also used to prepare standard, standard stock, Liothyronine stock, and resolution solutions for assay, and identification test according to given below monographs of the United States Pharmacopeia (USP):
- Thyroid
- Levothyroxine Sodium Tablets
- Liothyronine Sodium Tablets
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
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signalword
Danger
hcodes
Hazard Classifications
STOT RE 1
target_organs
Thyroid,Cardio-vascular system,Kidney
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
涉药品监管产品
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Sara Santos Bernardes et al.
Cell and tissue research, 357(3), 803-814 (2014-05-21)
The role of reactive oxygen species (ROS) in muscle protein hydrolysis and protein oxidation in thyrotoxicosis has not been explored. This study indicates that ROS play a role in skeletal muscle wasting pathways in thyrotoxicosis. Two experimental groups (rats) were
Akihiro Mouri et al.
Psychoneuroendocrinology, 48, 147-161 (2014-07-13)
Attention deficit/hyperactivity disorder (ADHD) has been reported in association with resistance to thyroid hormone, a disease caused by a mutation in the thyroid hormone receptor β (TRβ) gene. TRβ is a key protein mediating down-regulation of thyrotropin (TSH) expression by
Héctor F Escobar-Morreale et al.
The Journal of clinical endocrinology and metabolism, 90(8), 4946-4954 (2005-06-02)
Combined infusion of levothyroxine plus liothyronine, as opposed to levothyroxine alone, is the only way of restoring the concentrations of circulating TSH, T4, and T3 as well as those of both T4 and T3 in all tissues of thyroidectomized rats.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 1368008-250MG | 04061838731432 |