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1492200

USP

Palonosetron hydrochloride

Name: Palonosetron hydrochloride
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(3aS)-2-[(3S)-Quinuclidin-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride, (3aS)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-Benz[de]isoquinolin-1-one hydrochloride (1:1), RS 25259-197

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₂₄N₂O · HCl

CAS Number:

135729-62-3

Molecular Weight:

332.87

NACRES:

NA.24

PubChem Substance ID:

329750657

UNSPSC Code:

41116107

MDL number:

MFCD00939524

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Properties

grade

pharmaceutical primary standard

API family

palonosetron

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C1N([C@H]2C3CCN(CC3)C2)C[C@]4([H])C5=C1C=CC=C5CCC4.[H]Cl

InChI

1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17-;/m1./s1

InChI key

OLDRWYVIKMSFFB-SSPJITILSA-N

Gene Information

human ... HTR3A(3359)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Palonosetron hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Palonosetron is a potent and selective 5-HT3 receptor antagonist (Aloxi) used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

Palonosetron is a potent and selective 5-HT3 receptor antagonist.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c