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1535507

USP

Phenytoin sodium

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

5,5-Diphenylhydantoin sodium salt, 5,5-Diphenyl-2,4-imidazolidinedione, Phenytoin

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About This Item

Linear Formula:
C15H11N2O2Na
CAS Number:
630-93-3
Molecular Weight:
274.25
NACRES:
NA.24
PubChem Substance ID:
329750830
UNSPSC Code:
41116107
MDL number:
MFCD00069674
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grade

pharmaceutical primary standard

API family

phenytoin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[Na]N1C(=O)NC(C1=O)(c2ccccc2)c3ccccc3

InChI

1S/C15H12N2O2.Na/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12;/h1-10H,(H2,16,17,18,19);/q;+1/p-1

InChI key

FJPYVLNWWICYDW-UHFFFAOYSA-M

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

General description

Phenytoin sodium is an anti-epileptic drug, which belongs to the hydantoin family.

Application

Phenytoin sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.
Reduces incidence of grand mal seizures; appears to stabilize excitable membranes.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Courtenay M and Griffiths M
Independent and Supplementary Prescribing: An Essential Guide null
Lemke.LT and Williams.AD
Foye's Principles of Medicinal Chemistry (2012)
Maria B Rabaglino et al.
BMC genomics, 15, 1001-1001 (2014-11-21)
Major changes in gene expression occur in the fetal brain to modulate the function of this organ postnatally. Thus, factors can alter the genomics of the fetal brain, predisposing to neurological disorders later in life. We hypothesized that the physiological
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Global Trade Item Number

SKUGTIN
1535507-200MG04061838740915