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About This Item
Linear Formula:
(CH3CH2CH2)2CHCO2H
CAS Number:
Molecular Weight:
144.21
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
202-777-3
MDL number:
grade
pharmaceutical primary standard
API family
valproic acid
manufacturer/tradename
USP
refractive index
n20/D 1.425 (lit.)
bp
220 °C (lit.)
density
0.9 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
CCCC(C(O)=O)CCC
InChI
1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
InChI key
NIJJYAXOARWZEE-UHFFFAOYSA-N
Gene Information
human ... ALDH5A1(7915)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Valproic acid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Divalproex Sodium
- Divalproex Sodium Delayed-Release Capsules
- Divalproex Sodium Delayed-Release Tablets
- Divalproex Sodium Extended-Release Tablets
- Valproate Sodium Injection
- Valproic Acid
- Valproic Acid Capsules
Biochem/physiol Actions
Anticonvulsant that also has efficacy as a mood stabilizer in bipolar disorder
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1A - Skin Irrit. 2
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
231.8 °F - closed cup
flash_point_c
111 °C - closed cup
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Radu M Nanau et al.
Clinical biochemistry, 46(15), 1323-1338 (2013-06-25)
Valproic acid is a widely-used first-generation antiepileptic drug, prescribed predominantly in epilepsy and psychiatric disorders. VPA has good efficacy and pharmacoeconomic profiles, as well as a relatively favorable safety profile. However, adverse drug reactions have been reported in relation with
Mattias Linde et al.
The Cochrane database of systematic reviews, 6(6), CD010611-CD010611 (2013-06-26)
Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an
Ivana Rosenzweig et al.
Neuroscience and biobehavioral reviews, 36(8), 1848-1856 (2012-06-02)
Neuropsychiatric medications that directly alter the epigenome, such as valproic acid, can under certain conditions reactivate critical developmental periods and thus impact adult neuroconnectivity. In animal models valproic acid was shown to inhibit the process of postnatal myelination and to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 1708707-500MG | 04061838750532 |