V900343
L-Arginine
≥98%, Vetec™
Synonym(s):
(S)-2-Amino-5-guanidinopentanoic acid
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About This Item
Linear Formula:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
CAS Number:
Molecular Weight:
174.20
UNSPSC Code:
12352209
PubChem Substance ID:
EC Number:
200-811-1
Beilstein/REAXYS Number:
1725413
MDL number:
Product Name
L-Arginine, Vetec™, reagent grade, ≥98%
grade
reagent grade
product line
Vetec™
assay
≥98%
form
powder
color
white
mp
222 °C (dec.) (lit.)
SMILES string
N[C@@H](CCCNC(N)=N)C(O)=O
InChI
1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
InChI key
ODKSFYDXXFIFQN-BYPYZUCNSA-N
Application
- L-Arginine-Dependent Nitric Oxide Production in the Blood of Patients with Type 2 Diabetes: A Pilot, Five-Year Prospective Study.: This study examines the role of L-Arginine in nitric oxide production in diabetic patients, proposing its potential benefits for managing vascular complications in diabetes (Stoian et al., 2024).
Biochem/physiol Actions
Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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John Pernow et al.
Cardiovascular research, 98(3), 334-343 (2013-02-19)
Functional integrity of the vascular endothelium is of fundamental importance for normal vascular function. A key factor regulating endothelial function is the bioavailability of nitric oxide (NO). Recently, the enzyme arginase has emerged as an important regulator of NO production
Hartmut Grasemann et al.
Current pharmaceutical design, 18(5), 726-736 (2012-01-11)
The concentrations of nitric oxide are decreased in airways of patients with cystic fibrosis. The reasons for this nitric oxide deficiency are incompletely understood but may include reduced production from nitric oxide synthases due to decreased expression, the enzymes in
Yasutoshi Koga et al.
Biochimica et biophysica acta, 1820(5), 608-614 (2011-09-29)
The pathogenic mechanism of stroke-like episodes seen in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) has not been clarified yet. About 80% of MELAS patients have an A3243G mutation in the mitochondrial tRNA(Leu(UUR)) gene, which is the base
Global Trade Item Number
| SKU | GTIN |
|---|---|
| V900343-100G | 04061833469644 |
| V900343-500G | 04061833615089 |