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V900516

Bicinchoninic acid disodium salt hydrate

Name: Bicinchoninic acid disodium salt hydrate
Brand: VETEC

≥98% purity , reagent grade, powder

Synonym(s):

2,2′-Biquinoline-4,4′-dicarboxylic acid disodium salt, 4,4′-Dicarboxy-2,2′-biquinoline disodium salt, BCA, Disodium 2,2′-biquinoline-4,4′-dicarboxylate

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₁₀N₂Na₂O₄ · xH₂O

CAS Number:

979-88-4

Molecular Weight:

388.28 (anhydrous basis)

PubChem Substance ID:

329829897

UNSPSC Code:

12171500

MDL number:

MFCD10567219

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Properties

Product Name

Bicinchoninic acid disodium salt hydrate, Vetec^™, reagent grade, 98%

grade

reagent grade

product line

Vetec^™

assay

98%

form

powder

solubility

0.5% sodium bicarbonate: 50 mg/mL, colorless to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

O.[Na+].[Na+].[O-]C(=O)c1cc(nc2ccccc12)-c3cc(C([O-])=O)c4ccccc4n3

InChI

1S/C20H12N2O4.2Na.H2O/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;;/h1-10H,(H,23,24)(H,25,26);;;1H2/q;2*+1;/p-2

InChI key

FAFVGCAYKZKOPT-UHFFFAOYSA-L

Description

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

pcodes

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

flash_point_f

No data available

flash_point_c

No data available

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GSK3β is increased in adipose tissue and skeletal muscle from women with gestational diabetes where it regulates the inflammatory response.

Martha Lappas

PloS one, 9(12), e115854-e115854 (2014-12-30)

Infection and inflammation, through their ability to increase pro-inflammatory cytokines and chemokines and adhesion molecules, are thought to play a central role in the pathophysiology of insulin resistance and type 2 diabetes. Recent studies have shown that glycogen synthase kinase

Cyclic hypoxia does not alter RAD51 expression or PARP inhibitor cell kill in tumor cells.

Ramya Kumareswaran et al.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 116(3), 388-391 (2015-04-07)

Solid tumors contain regions of chronic and cyclic hypoxia. Chronic hypoxia can downregulate RAD51 and sensitize cells to PARP inhibition. Herein, we show that RAD51 expression, cell survival and toxicity to PARP inhibition is not affected under cyclic hypoxic conditions.

Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs.

Makon-Sébastien Njock et al.

Blood, 125(20), 3202-3212 (2015-04-04)

The blood contains high concentrations of circulating extracellular vesicles (EVs), and their levels and contents are altered in several disease states, including cardiovascular disease. However, the function of circulating EVs, especially the microRNAs (miRNAs) that they contain, are poorly understood.

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Global Trade Item Number

SKU	GTIN
V900516-5G	04061832346656
V900516-25G	04061832346649