900584
5-乙炔基-2′-脱氧尿苷
95%
别名:
EdU
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关于此项目
经验公式（希尔记法）:
C11H12N2O5
化学文摘社编号:
分子量:
252.22
MDL number:
UNSPSC Code:
12352208
NACRES:
NA.22
Assay:
95%
Form:
powder
Quality Level
assay
95%
form
powder
manufacturer/tradename
(BCN-001)
mp
206 °C
storage temp.
−20°C
SMILES string
OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(C#C)=C2)=O)=O)O1
InChI
1S/C11H12N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h1,4,7-9,14-15H,3,5H2,(H,12,16,17)/t7-,8+,9+/m0/s1
InChI key
CDEURGJCGCHYFH-DJLDLDEBSA-N
General description
5-乙炔基-2′-脱氧尿苷（EdU）是一种胸苷类似物，可掺入到细胞DNA中，以进行细胞增殖研究。所掺入的核苷类似物可以通过与荧光叠氮化物的铜催化点击反应来检测。
Application
5-乙炔基-2′-脱氧尿苷（EdU）用于：
有关Baseclick试剂盒的列表，参见：Baseclick试剂盒
- 在复制过程中标记新合成的DNA
- 细胞增殖试验研究
- 细胞周期分析
有关Baseclick试剂盒的列表，参见：Baseclick试剂盒
signalword
Danger
hcodes
Hazard Classifications
Muta. 1B - Repr. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Synthesis, susceptibility to enzymatic phosphorylation, cytotoxicity and in vitro antiviral activity of lipophilic pyrimidine nucleoside/carborane conjugates.
Bialek-Pietras M, et al.
Journal of Organometallic Chemistry, 865, 166-172 (2018)
Click chemistry as a reliable method for the high-density postsynthetic functionalization of alkyne-modified DNA.
Gierlich J, et al.
Organic Letters, 8(17), 3639-3642 (2006)
Site-directed spin-labeling of nucleic acids by click chemistry: detection of abasic sites in duplex DNA by EPR spectroscopy.
Jakobsen A, et al.
Journal of the American Chemical Society, 132(30), 10424-10428 (2010)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 900584-500MG | 04061833250372 |
| 900584-50MG | 04061833250389 |